Facts

Konrad Aden

Prof. Dr. med. Konrad Aden

Phone: +49(0)431-500-22455
E-Mail: k.aden@ikmb.uni-kiel.de
Website:
www.ikmb.uni-kiel.de/people/scientists/konrad-aden
Institute: Institute of Clinical Molecular Biology (IKMB) / Kiel University (CAU), I. Medical Department / University Medical Center Schleswig-Holstein (UKSH)
Address: Rosalind-Franklin-Str. 12, 24105 Kiel, Germany
Group: Junior Research Group Immunometabolism of Intestinal Inflammation and Systems Immunology

Konrad Aden holds an Else Kröner Clinician Scientist Professorship for Gastroenterology and Metabolomics at Kiel University and is a senior physician at the Department of Internal Medicine I at UKSH, Campus Kiel. He is the principal investigator of project 7. He leads the research group Intestinal Immunometabolism at the IKMB.

Special fields:

  • Gastroenterology
  • Translational IBD research
  • Immuno-metabolism of inflammation
  • Coordinator BMBF Juniorverbund “Try-IBD”

Research groups:

Project-related publications

P5

A gut bacterial signature in blood and liver tissue characterizes cirrhosis and hepatocellular carcinoma.

Maria Effenberger, Silvio Waschina, Christina Bronowski, Gregor Sturm, Oronzo Tassiello, Felix Sommer, Andreas Zollner, Christina Watschinger, Felix Grabherr, Ronald Gstir, Christoph Grander, Barbara Enrich, Reto Bale, Daniel Putzer, Angela Djanani, Alexander R Moschen, Heinz Zoller, Jan Rupp, Stefan Schreiber, Remy Burcelin, Cornelia Lass-Flörl, Zlatko Trajanoski, Georg Oberhuber, Philip Rosenstiel, Timon E Adolph, Konrad Aden, Herbert Tilg

PubMed (PMID: 37314752)
Hepatology communications
2023
P1

Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn’s disease.

Gabriela Rios Martini, Ekaterina Tikhonova, Elisa Rosati, Meghan Bialt DeCelie, Laura Katharina Sievers, Florian Tran, Matthias Lessing, Arne Bergfeld, Sophia Hinz, Susanna Nikolaus, Julia Kümpers, Anna Matysiak, Philipp Hofmann, Carina Saggau, Stephan Schneiders, Ann-Kristin Kamps, Gunnar Jacobs, Wolfgang Lieb, Jochen Maul, Britta Siegmund, Barbara Seegers, Holger Hinrichsen, Hans-Heinrich Oberg, Daniela Wesch, Stefan Bereswill, Markus M Heimesaat, Jan Rupp, Olaf Kniemeyer, Axel A Brakhage, Sascha Brunke, Bernhard Hube, Konrad Aden, Andre Franke, Iliyan D Iliev, Alexander Scheffold, Stefan Schreiber, Petra Bacher

PubMed (PMID: 37749331)
Nature medicine
2023

Prediction of Response to Systemic Corticosteroids in Active UC by Microbial Composition-A Prospective Multicenter Study.

Andreas Blesl, Philipp Wurm, Silvio Waschina, Hans Peter Gröchenig, Gottfried Novacek, Christian Primas, Walter Reinisch, Maximilian Kutschera, Constanze Illiasch, Barbara Hennlich, Pius Steiner, Robert Koch, Wolfgang Tillinger, Thomas Haas, Gerhard Reicht, Andreas Mayer, Othmar Ludwiczek, Wolfgang Miehsler, Karin Steidl, Lukas Binder, Simon Reider, Christina Watschinger, Stefan Fürst, Patrizia Kump, Alexander Moschen, Konrad Aden, Gregor Gorkiewicz, Christoph Högenauer

PubMed (PMID: 37463118)
Inflammatory bowel diseases
2023
P5

PUFA-induced metabolic enteritis as a fuel for Crohn’s disease.

Julian Schwärzler, Lisa Mayr, Arnau Vich Vila, Felix Grabherr, Lukas Niederreiter, Maureen Philipp, Christoph Grander, Moritz Meyer, Almina Jukic, Simone Tröger, Barbara Enrich, Nicole Przysiecki, Markus Tschurtschenthaler, Felix Sommer, Irmgard Kronberger, Jakob Koch, Richard Hilbe, Michael W Hess, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Nicole C Kaneider, Verena Wieser, Markus A Keller, Rinse K Weersma, Konrad Aden, Philip Rosenstiel, Richard S Blumberg, Arthur Kaser, Herbert Tilg, Timon E Adolph

PubMed (PMID: 35031299)
Gastroenterology (New York, N.Y. 1943)
2022
P5

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon.

Antonella Fazio, Dora Bordoni, Jan W P Kuiper, Saskia Weber-Stiehl, Stephanie T Stengel, Philipp Arnold, David Ellinghaus, Go Ito, Florian Tran, Berith Messner, Anna Henning, Joana P Bernardes, Robert Häsler, Anne Luzius, Simon Imm, Finn Hinrichsen, Andre Franke, Samuel Huber, Susanna Nikolaus, Konrad Aden, Stefan Schreiber, Felix Sommer, Gioacchino Natoli, Neha Mishra, Philip Rosenstiel

PubMed (PMID: 36271073)
Nature communications
2022
P1

A novel unconventional T cell population enriched in Crohn’s disease.

Elisa Rosati, Gabriela Rios Martini, Mikhail V Pogorelyy, Anastasia A Minervina, Frauke Degenhardt, Mareike Wendorff, Soner Sari, Gabriele Mayr, Antonella Fazio, Christel Marie Dowds, Charlotte Hauser, Florian Tran, Witigo von Schönfels, Julius Pochhammer, Maria A Salnikova, Charlot Jaeckel, Johannes Boy Gigla, Sanaz Sedghpour Sabet, Matthias Hübenthal, Esther Schiminsky, Stefan Schreiber, Philip C Rosenstiel, Alexander Scheffold, Paul G Thomas, Wolfgang Lieb, Bernd Bokemeyer, Maria Witte, Konrad Aden, Alexander Hendricks, Clemens Schafmayer, Jan-Hendrick Egberts, Ilgar Z Mamedov, Petra Bacher, Andre Franke

PubMed (PMID: 35264446)
Gut : journal of the British Society of Gastroenterology
2022

Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases.

Konrad Aden, Ateequr Rehman, Silvio Waschina, Wei-Hung Pan, Alesia Walker, Marianna Lucio, Alejandro Mena Nunez, Richa Bharti, Johannes Zimmerman, Johannes Bethge, Berenice Schulte, Dominik Schulte, Andre Franke, Susanna Nikolaus, Johann Oltmann Schroeder, Doris Vandeputte, Jeroen Raes, Silke Szymczak, Georg H Waetzig, Rainald Zeuner, Philippe Schmitt-Kopplin, Christoph Kaleta, Stefan Schreiber, Philip Rosenstiel

PubMed (PMID: 31326413)
Gastroenterology (New York, N.Y. 1943)
2019

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.

Konrad Aden, Florian Tran, Go Ito, Raheleh Sheibani-Tezerji, Simone Lipinski, Jan W Kuiper, Markus Tschurtschenthaler, Svetlana Saveljeva, Joya Bhattacharyya, Robert Häsler, Kareen Bartsch, Anne Luzius, Marlene Jentzsch, Maren Falk-Paulsen, Stephanie T Stengel, Lina Welz, Robin Schwarzer, Björn Rabe, Winfried Barchet, Stefan Krautwald, Gunther Hartmann, Manolis Pasparakis, Richard S Blumberg, Stefan Schreiber, Arthur Kaser, Philip Rosenstiel

PubMed (PMID: 30254094)
The journal of experimental medicine
2018

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