Facts

Prof. Dr. rer. nat. Christoph Kaleta

Phone: +49 (0)431-500-30340
E-Mail: c.kaleta@iem.uni-kiel.de
Website:
www.iem.uni-kiel.de/msb
Institute: Institute for Experimental Medicine (IEM) / Kiel University (CAU)
Address: Michaelisstr. 5, 24105 Kiel, Germany
Group: Medical Systems Biology

Christoph Kaleta is a professor for Medical Systems Biology at Kiel University and principle investigator of project Z. The main focus of his research group lies in metabolic modelling of host- and microbiota metabolism in the context of human diseases.

Special fields:

  • Host-microbiome interactions
  • Metabolic modelling
  • Integrative analysis of OMICs data
  • Systems Biology
  • Microbial community modelling

Research groups:

Project-related publications

Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis.

Finn Hinrichsen, Jacob Hamm, Magdalena Westermann, Lena Schröder, Kensuke Shima, Neha Mishra, Alesia Walker, Nina Sommer, Kenneth Klischies, Daniela Prasse, Johannes Zimmermann, Sina Kaiser, Dora Bordoni, Antonella Fazio, Georgios Marinos, Georg Laue, Simon Imm, Valentina Tremaroli, Marijana Basic, Robert Häsler, Ruth A Schmitz, Stefan Krautwald, Andrea Wolf, Bärbel Stecher, Philippe Schmitt-Kopplin, Christoph Kaleta, Jan Rupp, Fredrik Bäckhed, Philip Rosenstiel, Felix Sommer

PubMed (PMID: 34847376)
Cell metabolism
2021

Precision Nutrition in Chronic Inflammation.

Tobias J Demetrowitsch, Kristina Schlicht, Carina Knappe, Johannes Zimmermann, Julia Jensen-Kroll, Alina Pisarevskaja, Fynn Brix, Juliane Brandes, Corinna Geisler, Georgios Marinos, Felix Sommer, Dominik M Schulte, Christoph Kaleta, Vibeke Andersen, Matthias Laudes, Karin Schwarz, Silvio Waschina

PubMed (PMID: 33329569)
Frontiers in immunology
2020

Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases.

Konrad Aden, Ateequr Rehman, Silvio Waschina, Wei-Hung Pan, Alesia Walker, Marianna Lucio, Alejandro Mena Nunez, Richa Bharti, Johannes Zimmerman, Johannes Bethge, Berenice Schulte, Dominik Schulte, Andre Franke, Susanna Nikolaus, Johann Oltmann Schroeder, Doris Vandeputte, Jeroen Raes, Silke Szymczak, Georg H Waetzig, Rainald Zeuner, Philippe Schmitt-Kopplin, Christoph Kaleta, Stefan Schreiber, Philip Rosenstiel

PubMed (PMID: 31326413)
Gastroenterology (New York, N.Y. 1943)
2019

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.

Rosina Pryor, Povilas Norvaisas, Georgios Marinos, Lena Best, Louise B Thingholm, Leonor M Quintaneiro, Wouter De Haes, Daniela Esser, Silvio Waschina, Celia Lujan, Reuben L Smith, Timothy A Scott, Daniel Martinez-Martinez, Orla Woodward, Kevin Bryson, Matthias Laudes, Wolfgang Lieb, Riekelt H Houtkooper, Andre Franke, Liesbet Temmerman, Ivana Bjedov, Helena M Cochemé, Christoph Kaleta, Filipe Cabreiro

PubMed (PMID: 31474368)
Cell
2019

Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Peer Aramillo Irizar, Sascha Schäuble, Daniela Esser, Marco Groth, Christiane Frahm, Steffen Priebe, Mario Baumgart, Nils Hartmann, Shiva Marthandan, Uwe Menzel, Julia Müller, Silvio Schmidt, Volker Ast, Amke Caliebe, Rainer König, Michael Krawczak, Michael Ristow, Stefan Schuster, Alessandro Cellerino, Stephan Diekmann, Christoph Englert, Peter Hemmerich, Jürgen Sühnel, Reinhard Guthke, Otto W Witte, Matthias Platzer, Eytan Ruppin, Christoph Kaleta

PubMed (PMID: 29382830)
Nature communications
2018

Participating Institutes