Prof. Dr. rer. nat. Christoph Kaleta
Phone: +49 (0)431-500-30340
Institute: Institute for Experimental Medicine (IEM) / Kiel University (CAU)
Address: Michaelisstr. 5, 24105 Kiel, Germany
Group: Medical Systems Biology
Christoph Kaleta is a professor for Medical Systems Biology at Kiel University and principle investigator of project Z. The main focus of his research group lies in metabolic modelling of host- and microbiota metabolism in the context of human diseases.
- Host-microbiome interactions
- Metabolic modelling
- Integrative analysis of OMICs data
- Systems Biology
- Microbial community modelling
gapseq: informed prediction of bacterial metabolic pathways and reconstruction of accurate metabolic models.
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis.
Parkinson’s Disease and the Metal-Microbiome-Gut-Brain Axis: A Systems Toxicology Approach.
Antioxidants (Basel, Switzerland)
Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila.
Elucidating the Influence of Chromosomal Architecture on Transcriptional Regulation in Prokaryotes – Observing Strong Local Effects of Nucleoid Structure on Gene Regulation.
Frontiers in Microbiology
Defining the nutritional input for genome-scale metabolic models: A roadmap.
Precision Nutrition in Chronic Inflammation.
Frontiers in immunology
Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases.
Gastroenterology (New York, N.Y. 1943)
Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.
The functional repertoire contained within the native microbiota of the model nematode Caenorhabditis elegans.
The ISME journal
Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.
Gut dysbiosis with Bacilli dominance and accumulation of fermentation products precedes late-onset sepsis in preterm infants.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America