Facts

Prof. Dr. rer. nat. John Baines

Phone: +49(0)431-500-30310

Website:

www.iem.uni-kiel.de/de/evolutionaere-medizin

web.evolbio.mpg.de/evolgenomics

Institute: Institute for Experimental Medicine (IEM) / Kiel University (CAU), Max Planck Institute for Evolutionary Biology (MPI)

Address: Michaelisstr. 5, 24105 Kiel, Germany

Group: Evolutionary Medicine

John Baines serves as a professor in Evolutionary Genomics at Kiel University and is principle investigator of P10. He holds an SH Excellence Chair, is speaker of Clinician Scientist Program in Evolutionary Medicine and coordinates the function area Evolutionary Medicine of the master program Medical Life Science at Kiel University.

Special fields:

Evolution
Genomics
Host-microbiome interactions

Project-related publications

Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.

Giulia Pontarollo, Bettina Kollar, Amrit Mann, My Phung Khuu, Klytaimnistra Kiouptsi, Franziska Bayer, Inês Brandão, Valeriya V Zinina, Jennifer Hahlbrock, Frano Malinarich, Maximilian Mimmler, Sudhanshu Bhushan, Federico Marini, Wolfram Ruf, Meriem Belheouane, John F Baines, Kristina Endres, Scott M Reba, Verena K Raker, Carsten Deppermann, Christoph Welsch, Markus Bosmann, Natalia Soshnikova, Benoit Chassaing, Mattias Bergentall, Felix Sommer, Fredrik Bäckhed, Christoph Reinhardt

PubMed (PMID: 37414930)

Nature metabolism

2023

NOD2 influences trajectories of intestinal microbiota recovery after antibiotic perturbation.

Jacqueline Moltzau Anderson, Simone Lipinski, Felix Sommer, Wei-Hung Pan, Olivier Boulard, Ateequr Rehman, Maren Falk-Paulsen, Stephanie T Stengel, Konrad Aden, Robert Häsler, Richa Bharti, Sven Künzel, John F Baines, Mathias Chamaillard, Philip Rosenstiel

PubMed (PMID: 32289499)

Cellular and molecular gastroenterology and hepatology

2020

Gut dysbiosis with Bacilli dominance and accumulation of fermentation products precedes late-onset sepsis in preterm infants.

S Graspeuntner, S Waschina, S Künzel, N Twisselmann, T K Rausch, K Cloppenborg-Schmidt, J Zimmermann, D Viemann, E Herting, W Göpel, J F Baines, C Kaleta, J Rupp, C Härtel, J Pagel

PubMed (PMID: 30329017)

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

2018

Faecal microbiota composition associates with abdominal pain in the general population.

Fatemeh Hadizadeh, Ferdinando Bonfiglio, Meriem Belheouane, Marie Vallier, Sascha Sauer, Corinna Bang, Luis Bujanda, Anna Andreasson, Lars Agreus, Lars Engstrand, Nicholas J Talley, Joseph Rafter, John F Baines, Susanna Walter, Andre Franke, Mauro D’Amato

PubMed (PMID: 28765473)

Gut : journal of the British Society of Gastroenterology

2017

Evaluating the maintenance of disease-associated variation at the blood group-related gene B4galnt2 in house mice.

Marie Vallier, Maria Abou Chakra, Laura Hindersin, Miriam Linnenbrink, Arne Traulsen, John F Baines

PubMed (PMID: 28806915)

BMC evolutionary biology

2017

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.

Jun Wang, Louise B Thingholm, Jurgita Skiecevičienė, Philipp Rausch, Martin Kummen, Johannes R Hov, Frauke Degenhardt, Femke-Anouska Heinsen, Malte C Rühlemann, Silke Szymczak, Kristian Holm, Tönu Esko, Jun Sun, Mihaela Pricop-Jeckstadt, Samer Al-Dury, Pavol Bohov, Jörn Bethune, Felix Sommer, David Ellinghaus, Rolf K Berge, Matthias Hübenthal, Manja Koch, Karin Schwarz, Gerald Rimbach, Patricia Hübbe, Wei-Hung Pan, Raheleh Sheibani-Tezerji, Robert Häsler, Philipp Rosenstiel, Mauro D’Amato, Katja Cloppenborg-Schmidt, Sven Künzel, Matthias Laudes, Hanns-Ulrich Marschall, Wolfgang Lieb, Ute Nöthlings, Tom H Karlsen, John F Baines, Andre Franke

PubMed (PMID: 27723756)

Nature genetics

2016