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Multi-centered T cell repertoire profiling identifies alterations in the immune repertoire of individuals with inflammatory bowel disease across different disease stages

Largest-to-date T-cell receptor (TCR) alpha profiling across three different cohorts with inflammatory bowel diseases, identifies robust sets of disease-associated clonotypes and proposing a potential new therapeutic and etiologic leads.

Inflammatory bowel disease (IBD) remains incurable,read more

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