Data management, bioinformatics and statistics

Research group INF

Introduction

The INF project is the central data management and analysis project of miTarget. Four important demands (work packages 1-4) will be addressed:

WP1: an overall data management platform (iRODS) for metagenome data to keep all data organized, documented and searchable

WP2: scalable and reproducible bioinformatic software pipelines (Nextflow)for metagenome analyses

WP3: customized statistical methods to address project-specific research questions related to the microbiome as a therapeutic target arising from the individual subprojects.

Fig. 1: NGS & IT ressources

Aims

We here aim

  • To manage an overall data management platform (iRODS) for metagenome data to keep all data organized, documented and searchable
  • To develop scalable and reproducible bioinformatic software pipelines (Nextflow) for metagenome analyses
  • To customize statistical methods to address project-specific research questions related to the microbiome as a therapeutic target arising from the individual subprojects.
Fig. 2: Example of containerised bioinformatic workflows
Fig. 3: Statistical methods and support

Researchers

Other important members of INF

  • Dr. Sandra Freitag-Wolf
  • Dr. Thomas Möbius, postdoc (statistician)
  • Dr. Marc Höppner
  • Dr. Jan Kässens
  • Dr. Malte Rühlemann

Participating Institutes